Hormonal Factors and Risk of Psoriasis in Women: A Cohort Study.
نویسندگان
چکیده
Previous studies suggest that hormonal factors modulate the natural course of psoriasis in women. However, the association of hormonal factors with psoriasis risk has not been assessed using prospective data. We carried out a thorough prospective analysis on the topic in 163,763 women in the Nurses' Health Study I and II. Participants provided information on age at menarche, parity, menopause status, and exogenous hormone use (oral contraceptive and postmenopausal hormone therapy) over the follow-up. We ascertained 1,253 incident psoriasis cases over 2 million person-years. Psoriasis risk appeared to be higher in women with always irregular menstrual cycles in adulthood (multivariate-adjusted hazard ratio=1.32, 95% CI: 1.01-1.73, compared with regular cycles) and surgical menopause (hazard ratio=1.19, 95% CI: 1.01-1.40, compared with natural menopause). Hormone therapy had suggestive but insignificant associations with psoriasis risk. Our results suggest little evidence for hormonal factors and risk of psoriasis in women that need further investigation.
منابع مشابه
Cardiovascular risk factors in patients with psoriasis: A casecontrol study
Recent studies suggest that psoriasis may be an independent risk factor for the development of cardiovascular diseases. Myocardial infarction, pulmonary embolism, diabetes mellitus,hypertension, and dyslipidemia have been reported in patients with psoriasis Certain risk factors for cardiovascular diseases may be more prevalent among patients with psoriasis 3,4. The aim of this study was to defi...
متن کاملPnm-4: Role of Hormonal Factors and Use ofContraceptive Pills on Breast Cancer
Background: Large part of research related to reInternational Journal of Fertility & Sterility (IJFS), Vol 4, Suppl 1, Summer 2010 94 productivefactors in breast cancer risk before and after menopause, a study case - control is that it factors in deliberate and spontaneous abortion in the two groups of women with breast cancer (cases) and non-infected women (control group) study, described odds...
متن کاملPsoriasis and risk of type 2 diabetes among women and men in the United States: a population-based cohort study
Type 2 diabetes (T2D) shares some common risk factors with psoriasis. We evaluated the association between psoriasis and the risk of incident T2D among women and men in the United States in a mixed retrospective-prospective cohort study. A total of 184,395 participants were included from an older cohort of women (the Nurses' Health Study (NHS); 1996-2008), a younger cohort of women (NHS II; 199...
متن کاملPrevalence and risk factors of joint diseases in patients with Psoriasis referred to Razi Skin Hospital in Tehran
Background: Psoriatic arthropathy is a seronegative arthropathy seen in some patients with psoriasis, a self-limited and genetically determined skin disease. Objective: To determine the prevalence and risk factors of arthropathy in patients with psoriasis. Patients and Methods: In a prospective, cross-sectional study, psoriatic patients referred to Razi Skin Hospital in Tehran, Iran in 20...
متن کاملP-167: Risk Factors for Ectopic Pregnancy: A Case-Control Study
Background: Ectopic pregnancy (EP) is a common condition which presents a major health problem for women of childbearing age. This study aims to analyze and identify risk factors that have the potential for EP and evaluating the contribution of the risk factors associated EP. Materials and Methods: In this case control study, performed from 2006 to 2011 at Arash hospital, the casepatients were ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Acta dermato-venereologica
دوره 96 7 شماره
صفحات -
تاریخ انتشار 2016